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Cordycepin

Cordycepin

Basic Information

CAS No.: 73-03-0
Molecular Formula: C10H13N5O3
Molecular weight: 251.24

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Product Details

Cordycepin (73-03-0) is an adenosine analog lacking the hydroxyl at the 3’ position. Inhibits PARP1?and polyadenylation2. Displays anti-inflammatory effects1,3?and neuroprotective effects by inhibiting Aβ-induced apoptosis in hippocampal neurons4. Induces apoptosis in a variety of cancer cell lines5. Displays antiobesity effects.6?Inhibits cell senescence via activation of AMPK.7?Maintains stem cell pluripotency and increases iPS cell generation efficiency.8


Chemical Properties

PropertyValue

Melting point

225-229 °C

Alpha

D20 -47°; D27 -42°

Boiling point

394.4°C (rough estimate)

Density

1.2938 (rough estimate)

Refractive index

1.7610 (estimate)

Rtorage temp.

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Solubility

Soluble in DMSO (up to 25 mg/ml).

Form

Powder

Pka

13?+-.0.60(Predicted)

Color

White to Off-white

Biological source

Cordyceps militaris

λmax

260nm(EtOH)(lit.)

Merck

14,2529

BRN

35194

Stability

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

InChIKey

OFEZSBMBBKLLBJ-BAJZRUMYSA-N

CAS DataBase Reference

73-03-0(CAS DataBase Reference)

EPA Substance Registry System

Adenosine, 3'-deoxy- (73-03-0)


Safety Information

PropertyValue
Hazard symbolsXn, T
Hazard class codes40-36/37/38-25-20/21/22
Safety descriptions22-36-45-26
UN dangerous goods numberUN 2811
WGK Germany3
RTECS numberAU7358610
F10-21
Hazard class6.1
HS code29349990
Storage class6.1C - Combustible, acute toxicity Category 3
Toxic compounds or compounds causing chronic effects
Hazard class (category)Acute toxicity, Category 3, Dermal
Acute toxicity, Category 3, Inhalation
Acute toxicity, Category 3, Oral


Product Usage

Cordycepin is primarily used in research for its adenosine analog properties. It is widely applied in studies on apoptosis, inflammation, metabolism, and anti-aging via AMPK/mTOR pathways. Common applications include cancer biology, immunology, and neuroprotection. For lab use only. 

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