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Asiaticoside

Asiaticoside

Basic Information

CAS No.:16830-15-2
Molecular Formula: C48H78O19
Molecular Weight: 959.12

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Product Details

Asiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat a variety of ailments including dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. In various wound healing models, topical application (0.2-0.4%), injection (1 mg), or ingestion (1 mg/kg) of asiaticoside has been shown to increase hydroxyproline content, improve tensile strength, increase collagen synthesis and remodeling of the collagen matrix, promote epithelialization, stimulate glycosaminoglycan synthesis, and elevate antioxidant levels.


Chemical Properties
PropertyValue

Melting point

235-238°C

Alpha

D20 -14° (alc)

Boiling point

1017.5±65.0 °C(Predicted)

Density

1.44±0.1 g/cm3(Predicted)

Vapor pressure

0.001Pa at 160℃

Storage temp.

Under inert gas (nitrogen or Argon) at 2-8°C

Solubility

DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly)

Pka

12.50±0.70(Predicted)

Form

Solid

Color

Crystals

Water Solubility

99mg/L

InChIKey

WYQVAPGDARQUBT-KRQXBQLUNA-N

LogP

0.44 at 22℃

CAS DataBase Reference

16830-15-2(CAS DataBase Reference)


Safety Information

PropertyValue

Safety Statements

24/25

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

3

RTECS

YU9625000

F

1-10

HS Code

29389090


Product Usage

Asiaticoside, a prominent triterpene glycoside extracted from Centella asiatica, is a powerhouse ingredient in the dermo-cosmetic and regenerative medicine industries. Its most celebrated application is in wound healing and scar management, where it stimulates the synthesis of Type I collagen and enhances skin tensile strength. In the skincare sector, it is a key component of "Cica" products, formulated to soothe sensitive skin, repair the skin barrier, and accelerate the healing of acne lesions. Beyond topical use, Asiaticoside is highly valued in the pharmaceutical industry for its potent anti-inflammatory and neuroprotective properties, with ongoing research focusing on its potential in treating venous insufficiency and cognitive disorders. Additionally, its ability to inhibit oxidative stress makes it an essential active for anti-aging treatments, effectively reducing the appearance of wrinkles and improving overall skin elasticity.

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