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Arbutin

Arbutin

Basic Information

CAS No.: 497-76-7
Molecular Formula: C12H16O7
Molecular Weight: 272.25

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Product Details

Arbutin is a β-D-glucopyranoside HQ derivative and a plant-derived compound found in the dried leaves of several plant species, including blueberry, cranberry, bearberry, and pear trees. It suppresses tyrosinase activity without altering RNA expression.


Chemical Properties
PropertyValue

Melting point

195-198 °C

Alpha

-64 º (c=3)

Boiling point

375.31°C (rough estimate)

Density

1.3582 (rough estimate)

Refractive index

-65.5 ° (C=4, H2O)

Storage temp.

Inert atmosphere,Room Temperature

Solubility

H2O: 50 mg/mL hot, clear

Pka

10.10±0.15(Predicted)

Form

Solid

Color

White

Biological source

Synthetic or plant

Optical Rotation

[α]/D -64.0±2.0°, c = 3 in H2O

Water Solubility

10-15 g/100 mL at 20 ºC

Sensitive

Hygroscopic

Merck

14,773

BRN

89673

Stability

Stable. Hygroscopic - store under dry nitrogen.

InChIKey

BJRNKVDFDLYUGJ-RMPHRYRLSA-N

LogP

-1.350

CAS DataBase Reference

497-76-7(CAS DataBase Reference)

EPA Substance Registry System

.beta.-D-Glucopyranoside, 4-hydroxyphenyl (497-76-7)


Safety Information

PropertyValue

Hazard Codes

Xn

Risk Statements

20/21/22-36/37/38

Safety Statements

22-24/25-36-26

WGK Germany

3

RTECS

CE8863000

F

3-10-23

HS Code

29389090

Hazardous Substances Data

497-76-7(Hazardous Substances Data)


Product Usage

Arbutin, a naturally derived hydroquinone glucoside typically extracted from bearberry leaves, is a premier active ingredient in the global cosmetic and skincare industry. It is primarily utilized as a safe and effective skin-lightening agent in brightening serums, whitening creams, and spot-correction treatments. By competitively inhibiting tyrosinase activity, it effectively suppresses melanin production to fade hyperpigmentation, melasma, and post-inflammatory dark spots. In the personal care sector, Arbutin is highly valued for its dual functionality, offering both depigmenting effects and potent antioxidant properties that protect the skin against oxidative stress induced by UV radiation. Furthermore, its mild nature compared to synthetic alternatives makes it an ideal component for sensitive skin formulations and high-end dermo-cosmetics aimed at evening out skin tone and restoring a youthful, radiant complexion.

Factory Showcase

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Shipping And Transportation

详情-物流

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A6: For eligible products and destinations, we can help coordinate appropriate packaging, shipping documents, and logistics arrangements. Requirements depend on the product classification, carrier rules, and destination regulations.

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