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Alpha-Arbutin

Alpha-Arbutin

Basic Information

CAS No.: 84380-01-8
Molecular Formula: C12H16O7
Molecular weight: 272.25

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Product Details

Arbutin is naturally found in plant sources such as Bearberry, Cranberry and Mulberry, which essentially prevents the formation of melanin (the pigment that creates skin colour). The chemically synthesised version of this plant extract is known as Alpha Arbutin which is used as a topical skin brightening agent to treat sun spots, pigmentation and scars caused by sun damage and breakouts. It also has antioxidant properties, which protect the skin from potential sun damage. Along with Retinol, it is a fairly common ingredient in anti-ageing products to treat age spots, fine lines and wrinkles.


Chemical Properties

PropertyValue

Melting point

195-196°C

Boiling point

561.6±50.0 °C(Predicted)

Density

1.556±0.06 g/cm3(Predicted)

Storage temp.

2-8°C

Solubility

DMSO (Slightly), Methanol (Slightly)

Form

Solid

Pka

10.10±0.15(Predicted)

Color

White to Off-White

BRN

89675

InChI

InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/s3

InChIKey

BJRNKVDFDLYUGJ-ZIQFBCGOSA-N

SMILES

O(C1C=CC(O)=CC=1)[C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:8,9,10,12,14,r|

CAS DataBase Reference

84380-01-8(CAS DataBase Reference)


Product Usage

Alpha-Arbutin is a high-purity, water-soluble active ingredient and a functional derivative of hydroquinone, celebrated for its exceptional skin-brightening capabilities. Its primary application is in the premium dermo-cosmetic industry, where it serves as a safe and effective lightening agent in serums, creams, and masks. By inhibiting tyrosinase activity, it effectively blocks melanin biosynthesis, making it a gold standard for treating hyperpigmentation, age spots, and uneven skin tone. In the skincare sector, it is favored over its beta counterpart due to its superior stability and nine-fold higher efficiency in skin lightening. Furthermore, its antioxidant properties provide protection against UV-induced oxidative stress, often being formulated alongside Vitamin C or Hyaluronic Acid to enhance overall complexion radiance and hydration.

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