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L-Tryptophan

Name: L-Tryptophan
SKU: 0

Basic Information

CAS No.: 73-22-3
Molecular Formula: C11H12N2O2
Molecular Weight: 204.23

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Product Details

L-tryptophan is the L-enantiomer of tryptophan. It has a role as an antidepressant, a nutraceutical, a micronutrient, a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an erythrose 4-phosphate/phosphoenolpyruvate family amino acid, a proteinogenic amino acid, a tryptophan and a L-alpha-amino acid. It is a conjugate base of a L-tryptophanium.

Chemical Properties

Property	Value
Melting point	289-290 °C (dec.)(lit.)
Alpha	-31.1 º (c=1, H20)
Boiling point	342.72°C (rough estimate)
Density	1.34
Bulk density	400kg/m3
Refractive index	-32 ° (C=1, H2O)
Storage temp.	2-8°C
Solubility	20% NH3: 0.1 g/mL at 20 °C, clear, colorless
Form	Powder
Pka	2.46(at 25℃)
Color	White to yellow-white
PH	5.5-7.0 (10g/l, H2O, 20℃)
Odor	wh. cryst. or cryst. odorless powd., sl. bitter taste
Biological source	Non-animal source
Optical Rotation	[α]20/D 31.5±1°, c = 1% in H2O
Water Solubility	11.4 g/L (25 ºC)
Merck	14,9797
BRN	86197
Stability	Stable. Incompatible with strong acids, strong oxidizing agents.
InChIKey	QIVBCDIJIAJPQS-VIFPVBQESA-N
LogP	0.704 (est)
CAS DataBase Reference	73-22-3(CAS DataBase Reference)
NIST Chemistry Reference	L-Tryptophan(73-22-3)
EPA Substance Registry System	L-Tryptophan (73-22-3)
Absorption	cut-off at 326nm in 0.5 M HCl at 0.5M

Safety Information

Property	Value
Hazard Codes	Xi
Risk Statements	33-40-62-41-37/38-36/37/38-22
Safety Statements	24/25-36/37/39-36-26
WGK Germany	2
RTECS	YN6130000
F	8
TSCA	Yes
HS Code	29339990
Hazardous Substances Data	73-22-3(Hazardous Substances Data)
Toxicity	LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000).

Product Usage

L-Tryptophan is an essential amino acid and a vital precursor to serotonin and melatonin, making it indispensable in the nutraceutical and pharmaceutical industries. Its primary application is in dietary supplements designed to improve sleep quality, regulate mood, and alleviate anxiety. In infant nutrition, it is a mandatory additive in formulas to ensure healthy neurological development and sleep-wake cycles. The animal feed industry also utilizes L-Tryptophan extensively as a growth promoter and stress-reducer for livestock and aquaculture, enhancing feed efficiency. Furthermore, it serves as a high-value chemical intermediate in the synthesis of specialized drugs and biochemical reagents. In cosmetics, it is occasionally used in anti-aging formulations for its potential antioxidant properties and role in skin repair.

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L-Tryptophan

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