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L-Methionine

L-Methionine

Basic Information

CAS No.: 63-68-3
Molecular Formula: C5H11NO2S
Molecular Weight: 149.21

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Product Details

L-methionine is a sulfur-containing essential L-amino acid that is important in many body functions. Methionine is a dietary indispensable amino acid required for normal growth and development of humans, other mammals, and avian species. In addition to being a substrate for protein synthesis, it is an intermediate in transmethylation reactions, serving as the major methyl group donor.


Chemical Properties

PropertyValue

Melting point

284 °C (dec.)(lit.)

Alpha

23.25 º (c=2, 6N HCl)

Boiling point

393.91°C (estimate)

Density

1,34g/cm

Bulk density

550kg/m3

Refractive index

1.5216 (estimate)

Storage temp.

20-25°C

Solubility

1 M HCl: 0.5 M at 20 °C, clear, colorless

Pka

2.13(at 25℃)

Form

Solid

Color

White

Odor

Slight characteristic

PH

5-7 (10g/l, H2O, 20℃)

biological source

synthetic

Optical Rotation

[α]20/D +23.7±0.5°, c = 5% in 5 M HCl

Water Solubility

Soluble

λmax

λ: 260 nm Amax: 0.40λ: 280 nm Amax: 0.05

Merck

14,5975

BRN

1722294

Stability

Stable. Incompatible with strong oxidizing agents.

LogP

0.217 (est)

CAS DataBase Reference

63-68-3(CAS DataBase Reference)

NIST Chemistry Reference

L-Methionine(63-68-3)

EPA Substance Registry System

L-Methionine (63-68-3)


Safety Information

PropertyValue

Risk Statements

33

Safety Statements

24/25

WGK Germany

2

RTECS

PD0457000

F

10-23

TSCA

Yes

HS Code

29304010

Hazardous Substances Data

63-68-3(Hazardous Substances Data)

Toxicity

LD50 oral in rat: 36gm/kg


Product Usage

L-Methionine is an essential sulfur-containing amino acid that serves as a fundamental building block for protein synthesis and a key methyl donor in various metabolic pathways. In the animal feed industry, it is a critical additive, especially for poultry and swine, to balance amino acid profiles, promote healthy growth, and improve feather or fur quality. In the pharmaceutical sector, L-Methionine is utilized as an active ingredient in hepatoprotective drugs to support liver detoxification and treat fatty liver diseases. It is also a staple in the nutraceutical industry, where it is included in dietary supplements for hair, skin, and nail health, as well as formulations targeting joint support. Additionally, it serves as a high-value chemical intermediate in the synthesis of specialized flavorings and as a nutrient component in biomedical cell culture media.

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