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L-Isoleucine

Name: L-Isoleucine
SKU: 0

Basic Information

CAS No.: 73-32-5
Molecular Formula: C6H13NO2
Molecular Weight: 131.17

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Product Details

Crystalline leaflets or a white, crystalline powder having a bitter taste. It is soluble in 25 parts of water, slightly soluble in hot alcohol, and soluble in diluted mineral acids and in alkaline solutions. It sublimes at between 168°C and 170°C, and melts with decomposition at about 284°C. The pH of a 1 in 100 solution is between 5.5 and 7.0.

Absolute: The absolute is prepared by alcoholic extraction of the concrete in approximately 55 to 60% yields. The absolute consists of a semisolid, olive-green mass with a characteristic ambergris odor.

Chemical Properties

Property	Value
Melting point	288 °C (dec.) (lit.)
Alpha	41 º (c=4, 6N HCl)
Boiling point	225.8±23.0 °C(Predicted)
Bulk density	470kg/m3
Density	1.2930 (estimate)
FEMA	4675 \| L-ISOLEUCINE
Refractive index	40.5 ° (C=4, 6mol/L HCl)
Fp	168-170°C
Storage temp.	Store below +30°C.
Solubility	1 M HCl: 50 mg/mL
Form	Powder
Pka	2.32, 9.76(at 25℃)
Color	White to Off-white
Odor	odorless
PH	5.5-6.5 (40g/l, H2O, 20℃)
Biological source	Synthetic
Optical Rotation	[α]20/D +41.0±1°, c = 5% in 6 M HCl
Water Solubility	41.2 g/L (50 ºC)
λmax	λ: 260 nm Amax: 0.07λ: 280 nm Amax: 0.05
JECFA Number	2118
Merck	14,5179
Sublimation	168-170 ºC
BRN	1721792
InChIKey	AGPKZVBTJJNPAG-WHFBIAKZSA-N
LogP	0.80
CAS DataBase Reference	73-32-5(CAS DataBase Reference)
NIST Chemistry Reference	Isoleucine(73-32-5)
EPA Substance Registry System	L-Isoleucine (73-32-5)

Safety Information

Property	Value
Hazard Codes	Xn
Risk Statements	40
Safety Statements	24/25-36-22
WGK Germany	3
RTECS	NR4705000
TSCA	Yes
HS Code	29224995
Hazardous Substances Data	73-32-5(Hazardous Substances Data)
Toxicity	LD50 intraperitoneal in rat: 6822mg/kg

Product Usage

L-Isoleucine is an essential branched-chain amino acid (BCAA) that plays a critical role in muscle metabolism, immune function, and hemoglobin synthesis. In the sports nutrition industry, it is a key component of BCAA formulations, working synergistically with leucine and valine to promote muscle recovery after intense exercise and prevent muscle breakdown. The pharmaceutical sector utilizes high-purity L-Isoleucine as a vital ingredient in parenteral and enteral nutrition infusions, providing essential metabolic support for patients recovering from trauma or surgery. In food science, it is used as a nutritional fortifier and flavor enhancer in specialized diets. Additionally, it serves as a high-value chemical intermediate in the synthesis of specialized peptides and surfactants. In the animal feed industry, it is increasingly used to optimize the amino acid profile in livestock diets to ensure healthy growth and efficient feed conversion.

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L-Isoleucine

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