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DL-Valine

DL-Valine

Basic Information

CAS No.: 516-06-3
Molecular Formula: C5H11NO2
Molecular Weight: 117.15

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Product Details

The molecular formula of DL-valine is C₅H₁₁NO₂, and its molecular weight is approximately 117.15. It has alternative names such as DL-α -aminoisovaleric acid and DL-2-amino3-methylbutyric acid. It appears as a white crystalline powder, with a melting point of approximately 295℃ and a boiling point of 213.6°C at 760 mmHg. The specific rotation is -0.6 to +0.6° (20°C/D)(c=8, HCl), it is hygroscopic and soluble in water.


Chemical Properties
PropertyValue

Melting point

295 °C (dec.) (lit.)

Alpha

-0.6~+0.6° (20℃/D)(c=8, HCl)

Boiling point

213.6±23.0 °C(Predicted)

Density

1.31

FEMA

3444 | D,L-VALINE

Refractive index

1.4650 (estimate)

Storage temp.

Keep in dark place,Inert atmosphere,Room temperature

Solubility

Water (Slightly, Sonicated)

Pka

pK1:2.32(+1);pK2:9.61(0) (25°C)

Form

Crystalline Powder

Color

White

Odor

Odorless

Odor Type

Odorless

Biological source

synthetic

Water Solubility

68 g/L

JECFA Number

1426

Merck

14,9909

BRN

506689

LogP

0.29

CAS DataBase Reference

516-06-3(CAS DataBase Reference)

NIST Chemistry Reference

DL-Valine(516-06-3)

EPA Substance Registry System

Valine (516-06-3)


Safety Information

PropertyValue

Hazard Codes

Xn

Risk Statements

40

Safety Statements

22-24/25-36

WGK Germany

3

RTECS

YV9355500

TSCA

Yes

HS Code

29224995


Product Usage

DL-Valine is an essential branched-chain amino acid (BCAA) produced as a racemic mixture of the D and L isomers, widely used in the biochemical and pharmaceutical industries. While L-valine is the biologically active form for protein synthesis, the DL-form serves as a cost-effective building block in organic synthesis and the production of specialized chemical intermediates. In the pharmaceutical sector, it is utilized in the synthesis of various drugs, including antihypertensive agents and antiviral medications. It is also an important component in cell culture media, providing necessary nutrients for the growth of microorganisms and mammalian cells in laboratory settings. Additionally, DL-Valine finds applications in the food and cosmetic industries as a flavor precursor and skin-conditioning agent, often used in research and development to study amino acid metabolism and enzyme specificity.

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