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Cholesterol

Name: Cholesterol
SKU: 0

Basic Information

CAS No.: 57-88-5
Molecular Formula: C27H46O
Molecular Weight: 386.65

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Product Details

Cholesterol is a waxy, fatty substance that exists in all cells of the body. It is produced in the liver, but can also be found in some foods. Cholesterol is essential for the normal functioning of the body as it helps in the production of hormones, vitamin D and bile acids. Cholesterol is carried in the blood through proteins, and proteins and cholesterol combine through proteins, which are called lipoproteins.

Chemical Properties

Property	Value
Melting point	148-150 °C
Alpha	-36 º (c=2, dioxane)
Boiling point	360 °C
Density	1.06
Refractive index	1.5250 (estimate)
Fp	250 °C
Storage temp.	-20°C
Solubility	H2O: 0.002 mg/mL
Form	Powder
pka	15.03±0.70(Predicted)
color	White
Specific Gravity	1.067
Odor	wh. or faintly yel. pearly granules or crystals, almost odorless
Biological source	Synthetic
Optical Rotation	-40.201°(C=0.01g/ml CHCL3)
Water Solubility	Negligible
Merck	14,2201
BRN	1915888
Dielectric constant	2.9（Ambient）
InChIKey	HVYWMOMLDIMFJA-DPAQBDIFSA-N
LogP	9.619 (est)
CAS DataBase Reference	57-88-5(CAS DataBase Reference)
NIST Chemistry Reference	Cholesterol(57-88-5)
IARC	3 (Vol. 31, Sup 7) 1987
EPA Substance Registry System	Cholesterol (57-88-5)

Safety Information

Property	Value
Hazard Codes	Xn,Xi
Risk Statements	10-48/20/22-40-38-22-36/37/38-67-36/38-20-63
Safety Statements	24/25-22-36/37-36-26
RIDADR	UN 1170 3/PG 3
WGK Germany	1
RTECS	FZ8400000
TSCA	Yes
HS Code	2906 13 10
HazardClass	IRRITANT
Hazardous Substances Data	57-88-5(Hazardous Substances Data)
Toxicity	Present in all parts of the animal body; concentrated in spinal cord, brain, skin secretions, and gallstones. An unsaturated, unsaponifiable alcohol (m.p. 149℃). It is synthesized in the body from ethanoate units; its metabolism is regulated by a specific set of enzymes. It is the parent compound of many other steroids and its presence in high concentrations in the blood is suspected as being a contributory factor in cardiovascular disease.

Product Usage

Cholesterol is a vital lipid and a fundamental structural component of cell membranes, widely utilized in the pharmaceutical and cosmetic industries. Its primary application is in the production of liposomes, which serve as advanced drug delivery systems to enhance the stability and absorption of active ingredients. In the pharmaceutical sector, it is a critical precursor for synthesizing Vitamin D3 and various steroid hormones. In cosmetics and skincare, cholesterol is a key ingredient in "skin-identical" formulations, helping to restore the skin barrier, improve moisture retention, and provide anti-aging benefits. Additionally, high-purity cholesterol is used in biotechnology as a cell culture supplement to support the growth of specialized cell lines and in the shrimp feed industry as an essential nutrient for crustacean growth and molting.

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Cholesterol

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