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Kojic acid

Name: Kojic acid
SKU: 0

Basic Information

CAS No.: 501-30-4
Molecular Formula：C6H6O4
Molecular weight：142.11

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Product Details

Kojic acid (CAS# 501-30-4) is a natural compound produced by microbial fermentation and is commonly found in the metabolites of Aspergillus and penicillium fungi. The chemical name was 5-hydroxy-2-hydroxymethyl-4h-pyrano-4-one. The molecular form was ₆. H₆O₄, and the molecular weight was 142.11. Kojic acid has a certain acidity and is relatively stable in acidic and neutral environments. It can chelate with metal ions and affect the activity of some enzymes, especially related to tyrosinase, which can reduce the production of melanin by inhibiting the activity of the enzyme, and is often used in the field of whitening skin care. In the food industry, due to its antioxidant properties, it can prevent food Browning and extend the shelf life.

Chemical Properties

Property	Value
Melting point	152-155 °C (lit.)
Boiling point	179.65°C (rough estimate)
Density	1.1712 (rough estimate)
Refractive index	1.4434 (estimate)
Storage temp.	Store below +30°C.
Solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
Form	Crystalline Powder
Pka	7.9(at 25℃)
Color	White to beige-brown
Water Solubility	SOLUBLE
λmax	269nm(CHCl3)(lit.)
Merck	14,5317
BRN	120895
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
LogP	-0.640
CAS DataBase Reference	501-30-4(CAS DataBase Reference)
NIST Chemistry Reference	5-Hydroxy-2-(hydroxymethyl)-4h-pyran-4-one(501-30-4)
IARC	3 (Vol. 79) 2001
EPA Substance Registry System	Kojic acid (501-30-4)

Safety Information

Property	Value
Hazard symbol	Xn
Hazard class codes	40-68
Safety descriptions	22-24/25-36/37-36
WGK Germany	3
RTECS number	UQ0875000
HS code	29329995
Storage class	11 - Combustible solids
Hazardous substances data	501-30-4 (Hazardous Substances Data)

Product Usage

Kojic acid is a natural chelation agent derived from various fungi, primarily known for its exceptional ability to inhibit melanin production. Its most prominent application is in the cosmetic industry, where it serves as a key ingredient in skin-lightening creams, serums, and soaps to treat hyperpigmentation, age spots, and melasma. In the food industry, it acts as a natural preservative and antioxidant, preventing enzymatic browning in fruits and seafood, particularly in maintaining the vibrant color of shrimp and crabs. Furthermore, Kojic acid is utilized in the pharmaceutical sector as an intermediate for synthesizing antibiotic and analgesic drugs. In agriculture, it is employed as a specialized pesticide stabilizer and a growth promoter due to its unique chemical reactivity and safety profile.

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Kojic acid

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