Phone：+86 15610166958
Email：fei@jnbychemicals.com
WhatsApp：+86 15610166958

  • Products

    Chemical Products for Diverse Industrial Applications

‹

  • Pagoclone
  • Pagoclone
  • Pagoclone

›

Pagoclone

Pagoclone

Basic Information

CAS No.: 133737-48-1
Molecular Formula: C23H22ClN3O2
Molecular weight: 407.89

Can't Find The Product You Need?

Tell Us Your Product Requirements, Specifications And Target Industry, Our Professional Team Will Reply You Within 24 Hours.

Contact Us
Email
Phone
WhatsApp

Navigation

Send Us A Message

Product Details

Pagolone is a specific GABA (Gamma-aminobutyric acid) receptor modulator that can reduce stuttering. Pagolone is a novel cyclopyrrolone that acts as a partial GABA (A) receptor agonist.


Chemical Properties

PropertyValue

Boiling point

582.1±50.0 °C(Predicted)

density

1.273±0.06 g/cm3(Predicted)

pka

1.62±0.30(Predicted)

InChI

InChI=1S/ C23H22ClN3O2/ c1-14(2) 7-10-16(28) 13-19-17-5-3-4-6-18(17) 23(29) 27(19)21-12-9-15-8-11-20 (24) 25-22(15) 26-21/ h3-6,8-9,11-12, 14, 19H, 7,10, 13H2, 1-2H3

InChIKey

HIUPRQPBWVEQJJ-UHFFFAOYSA-N

SMILES

C1(=O)C2= C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1= CC=C2C(=N1)N=C(Cl)C=C2


Product Usage

Pagoclone is a non-benzodiazepine anxiolytic compound belonging to the cyclopyrrolone family. As a selective GABA-A receptor partial agonist, its primary pharmaceutical application has been the focus of clinical research for treating generalized anxiety disorder (GAD) and panic disorders. Unlike traditional benzodiazepines, pagoclone is designed to provide anti-anxiety effects with significantly reduced sedative and amnestic side effects. Furthermore, it has gained international attention for its potential application in treating persistent developmental stuttering, with clinical trials exploring its ability to improve speech fluency. In the research sector, it serves as a critical reference standard for studying receptor subtype selectivity and the development of next-generation social ligands.

Factory Showcase

详情-工厂

Shipping And Transportation

详情-物流

FAQ

Q1: What information should I include in my inquiry?

A1: Please provide the product name, purity or grade, required quantity, packaging, application, destination, and any documentation requirements. More complete information helps us prepare an accurate quotation.


Q2: Can I request a sample?
A2: Samples may be available for selected products. Please provide the required grade, sample quantity, application, and delivery details so we can confirm availability and shipping arrangements.


Q3: What product documents can you provide?
A3: Depending on the product, available documents may include a COA, SDS, TDS, specifications, and packing information. Please confirm your documentation requirements before ordering.


Q4: Can you provide customized specifications or packaging?
A4: Customization may be available for selected products, including product specifications, packaging sizes, and labeling. Feasibility and minimum order requirements are evaluated individually.

 

Q5: How long does delivery take?

A5: Delivery time depends on product availability, order quantity, shipping method, destination, and customs procedures. An estimated schedule will be Q6: provided after the order requirements are confirmed.

 

Q6: Can you arrange the shipment of regulated chemicals?

A6: For eligible products and destinations, we can help coordinate appropriate packaging, shipping documents, and logistics arrangements. Requirements depend on the product classification, carrier rules, and destination regulations.

Contact Us

Related Recommendations