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Tween 80

Tween 80

Basic Information

CAS No.: 9005-65-6
Molecular Formula: C24H44O6
Molecular Weight: 428.60

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Product Details

Polyoxyethylene sorbitan fatty acid esters, often commercially known as "Tween", appear as yellow to amber viscous liquids, pastes or waxy solids (for example, Tween 20 is a liquid, Tween 60 is a paste, and Tween 85 is a viscous liquid) due to the different lengths of the fatty acid chain. They have no peculiar smell or a slight special odor. It is readily soluble in polar solvents such as water, ethanol and ethylene glycol, but poorly soluble in non-polar solvents such as mineral oil and vegetable oil.


Chemical Properties
PropertyValue
Melting point

-25 °C

Boiling point

>100°C

Density

1.08 g/mL at 20 °C

Vapor pressure

<1 mm Hg ( 20 °C)

Refractive index

N20/D1.473

FEMA

2917 | POLYSORBATE 80

Fp

>230 °F

Storage temp.

-20°C

Solubility

DMSO (Soluble), Methanol (Slightly)

Form

Viscous liquid

Color

Amber

Specific Gravity

1.080 (25/4℃)

PH Range

6

Odor

Mild alcoholic

PH

5-7 (50g/l, H2O, 20℃)

Odor Type

Alcoholic

Biological source

Synthetic

Water Solubility

5-10 g/100 mL at 23 ºC

Merck

14,7582

Hydrophilic-Lipophilic Balance (HLB)

10

LogP

4.392 (est)

EPA Substance Registry System

Polysorbate 80 (9005-64-5)



Safety Information

PropertyValue
Hazard symbolXi
Hazard class codes22-36/37/38-37/38-41
Safety descriptions24/25-36/37/39-36-26
WGK Germany1
RTECS numberWG2934000
F3
TSCATSCA listed
HS code34021300
Storage class10 - Combustible liquids
Hazardous substances data9005-65-6 (Hazardous Substances Data)
ToxicityLD50 in mice, rats (ml/kg): 7.5, 6.3 i.p. (Varma)


Product Usage

Tween 80, also known as Polysorbate 80, is a widely used nonionic surfactant applied in food, pharmaceutical, cosmetic, and industrial fields. In the food industry, it acts as an emulsifier and stabilizer to improve product uniformity and texture. In pharmaceuticals, it helps enhance the solubility and dispersion of active ingredients. In cosmetics, it is commonly used in lotions and creams to improve formulation stability and user experience. It also serves as a wetting and dispersing agent in industrial applications, offering good safety and compatibility.

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